N-nonyloxypentyl-L-deoxynojirimycin reduces Stenotrophomonas maltophilia virulence in vitro and in Galleria mellonella infection model

IntroductionStenotrophomonas maltophilia is an opportunistic pathogen able to resist multiple classes of antibiotics and form robust biofilms, making it difficult to treat.MethodsThe antimicrobial and anti-virulence activity of the iminosugar N-nonyloxypentyl-L-deoxynojirimycin (L-NPDNJ) against S....

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Auteurs principaux:	Maria Stabile, Anna Esposito, Antonella Migliaccio, Leandra Sepe, Rosaria Artiano, Antonella Ricca, Vita Dora Iula, Raffaele Zarrilli, Annalisa Guaragna, Eliana De Gregorio
Format:	Artigo
Langue:	Inglês
Publié:	Frontiers Media S.A. 2026-05-01
Collection:	Frontiers in Microbiology
Sujets:	adhesion inhibition anti-virulence drug biofilm eradication iminosugars L-deoxynojirimycin proteases reduction
Accès en ligne:	https://www.frontiersin.org/articles/10.3389/fmicb.2026.1835243/full
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