ATF3 links endoplasmic reticulum stress to ferroptosis via transcriptional activation of ALOX12 in benzene-induced hematotoxicity

As a Class I human carcinogen ubiquitous in both industrial and household environments, benzene can cause hematopoietic damage even at low concentrations. However, its precise hematological toxicological molecular mechanism remains incompletely understood. Here, we demonstrate that hydroquinone (HQ)...

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Auteurs principaux:	HuaFeng Zeng, YuXi Li, HongTing Zhao, Lin Chen, Lin Xu, ShaoYing Wang, YuFan Zhang, HaoChen Wang, ShuYun Huang, Yunqiang Xu, Chunnian You, Lei Sun, FengZhen Cui, Huanwen Tang
Format:	Artigo
Langue:	Inglês
Publié:	Elsevier 2026-05-01
Collection:	Ecotoxicology and Environmental Safety
Sujets:	Hydroquinone Endoplasmic reticulum stress Ferroptosis ATF3 Hematotoxicity
Accès en ligne:	http://www.sciencedirect.com/science/article/pii/S0147651326004598
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