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A Shiga Toxin B-Subunit-Based Lectibody Boosts T Cell Cytotoxicity towards Gb3-Positive Cancer Cells

Aberrant glycosylation plays a crucial role in tumour progression and invasiveness. Tumour-associated carbohydrate antigens (TACAs) represent a valuable set of targets for immunotherapeutic approaches. The poor immunogenicity of glycan structures, however, requires a more effective and well-directed...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Hauptverfasser: Jana Tomisch, Vincent Busse, Francesca Rosato, Olga N. Makshakova, Pavel Salavei, Anna-Sophia Kittel, Emilie Gillon, Levin Lataster, Anne Imberty, Ana Valeria Meléndez, Winfried Römer
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI AG 2023-07-01
Schriftenreihe:Cells
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Online-Zugang:https://www.mdpi.com/2073-4409/12/14/1896
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