Single-molecule measurements of bacteriophage lambda DNA packaging using purified terminase motor proteins and E. coli integration host factor

Abstract Biomotor-driven DNA packaging is a key step in the life cycle of many viruses. We previously developed single-molecule methods using optical tweezers to measure packaging dynamics of the bacteriophage lambda motor. The lambda system is more complex than others examined via single-molecule a...

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Библиографические подробности

Главные авторы:	Brandon Rawson, Qin Yang, Carlos E. Catalano, Douglas E. Smith
Формат:	Artigo
Язык:	Inglês
Опубликовано:	Nature Portfolio 2025-02-01
Серии:	Scientific Reports
Предметы:	Molecular motor Viral DNA packaging Optical tweezers Single-molecule biophysics Terminase holoenzyme
Online-ссылка:	https://doi.org/10.1038/s41598-024-74915-2
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