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Circulating nitric oxide pathway metabolites in heart failure with preserved ejection fraction: a sex-stratified cross-sectional analysis

Abstract Background Heart failure with preserved ejection fraction (HFpEF) is more prevalent in women, who often present with earlier onset and greater severity of vascular and endothelial dysfunction. Nitric oxide (NO) is a key contributor to vascular health, and several NO-related metabolites are...

Ausführliche Beschreibung

Gespeichert in:
Hauptverfasser: Sophia Marie-Theres Dinges, Edzard Schwedhelm, Flavia Baldassarri, Bernhard Haller, Andreas B. Gevaert, Rainer Böger, Ephraim B. Winzer, Frank Edelmann, Ulrik Wisløff, Volker Adams, Burkert Pieske, Emeline M. Van Craenenbroeck, Martin Halle, Susanna M. Hofmann, Stephan Mueller-Stegner
Format: Artigo
Sprache:Inglês
Veröffentlicht: BMC 2026-06-01
Schriftenreihe:Biology of Sex Differences
Schlagworte:
HFpEF
nitric oxide
endothelial dysfunction
vascular function
SDMA
ADMA
Online-Zugang:https://doi.org/10.1186/s13293-026-00940-7
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