Identification of New Natural DNA G-Quadruplex Binders Selected by a Structure-Based Virtual Screening Approach
The G-quadruplex DNA structures are mainly present at the terminal portion of telomeres and can be stabilized by ligands able to recognize them in a specific manner. The recognition process is usually related to the inhibition of the enzyme telomerase indirectly involved and over-expressed in a high...
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| Hlavní autoři: | , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
MDPI AG
2013-09-01
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| Edice: | Molecules |
| Témata: | |
| On-line přístup: | http://www.mdpi.com/1420-3049/18/10/12051 |
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