Syndecan-1 Promotes <named-content content-type="genus-species">Streptococcus pneumoniae</named-content> Corneal Infection by Facilitating the Assembly of Adhesive Fibronectin Fibrils

ABSTRACT Subversion of heparan sulfate proteoglycans (HSPGs) is thought to be a common virulence mechanism shared by many microbial pathogens. The prevailing assumption is that pathogens co-opt HSPGs as cell surface attachment receptors or as inhibitors of innate host defense. However, there are few...

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Egile Nagusiak:	Akiko Jinno, Atsuko Hayashida, Howard F. Jenkinson, Pyong Woo Park
Formatua:	Artigo
Hizkuntza:	Inglês
Argitaratua:	American Society for Microbiology 2020-12-01
Saila:	mBio
Gaiak:	extracellular matrix host-pathogen interactions keratitis proteoglycans syndecans
Sarrera elektronikoa:	https://journals.asm.org/doi/10.1128/mBio.01907-20
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