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Cyclic N-locked indolicidin analogues with antimicrobial activity: Effect of ring size and fatty acid acylation

Novel antimicrobial drugs are in high demand due to the increasing emergence of multi-drug resistant bacteria. In recent years, much attention has been given to natural occurring antimicrobial peptides (AMPs) such as indolicidin (ILPWKWPWWPWRR-NH2). In this study, 19 cyclic N-locked indolicidin anal...

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Prif Awduron: Abdullah Lone, Josefine Eilsø Nielsen, Peter W. Thulstrup, Reidar Lund, Paul Robert Hansen, Håvard Jenssen
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Elsevier 2022-12-01
Cyfres:European Journal of Medicinal Chemistry Reports
Pynciau:
Antimicrobial peptides
Cyclic antimicrobial peptides
Cyclic indolicidin
Cyclic lipopeptides
Circular dichroism
Small-angle X-ray scattering
Mynediad Ar-lein:http://www.sciencedirect.com/science/article/pii/S2772417422000528
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