Development of a Human B7-H3-Specific Antibody with Activity against Colorectal Cancer Cells through a Synthetic Nanobody Library

Nanobodies have emerged as promising tools in biomedicine due to their single-chain structure and inherent stability. They generally have convex paratopes, which potentially prefer different epitope sites in an antigen compared to traditional antibodies. In this study, a synthetic phage display nano...

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Principais autores:	Jingxian Li, Bingjie Zhou, Shiting Wang, Jiayi Ouyang, Xinyi Jiang, Chenglin Wang, Teng Zhou, Ke-wei Zheng, Junqing Wang, Jiaqi Wang
Format:	Artigo
Jezik:	Inglês
Izdano:	MDPI AG 2024-04-01
Serija:	Bioengineering
Teme:	synthetic library nanobody phage display B7-H3 ADCC
Online dostop:	https://www.mdpi.com/2306-5354/11/4/381
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