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Study of the Mechanism of Astragali Radix in Treating Type 2 Diabetes Mellitus and Its Renal Protection Based on Enzyme Activity, Network Pharmacology, and Experimental Verification

Astragali Radix (AR) is a common Chinese medicine and food. This article aims to reveal the active role of AR in treating Type 2 diabetes mellitus (T2DM) and its renal protective mechanism. The hypoglycemic active fraction was screened by α-glucosidase and identified by UPLC-QE-Orbitrap-MS spectrome...

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Principais autores: Chunnan Li, Kaiyue Zhang, Lu Liu, Jiaming Shen, Yuelong Wang, Yiying Tan, Xueqin Feng, Wanjie Liu, Hui Zhang, Jiaming Sun
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2023-12-01
coleção:Molecules
Assuntos:
Astragali Radix
T2DM
network pharmacology
UPLC-QE-Orbitrap-MS
mechanism
Acesso em linha:https://www.mdpi.com/1420-3049/28/24/8030
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