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The causal relationship between obstructive sleep apnea and otitis media: a bidirectional Mendelian randomization study

Obstructive sleep apnea (OSA) is manifested as periodic collapse of the upper airway during sleep. Otitis media is a spectrum of infectious and inflammatory diseases involving the middle ear. In this study, we sought to determine the causal effect of OSA on otitis media using a bidirectional, two-sa...

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Principais autores: Ruixin Guo, Yifan Zhang, Yijie Chen, Wenqi Sha, Wanyi Kou, Chensi Xu, Yuran Lei, Ningrui Zhang, Liu Yang, Yun Guo, Huihui Zhang, Zhenghui Wang
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2025-11-01
Serier:Experimental Biology and Medicine
Fag:
obstructive sleep apnea
otitis media
mendelian randomization
sleep disorder
twosample mendelian randomization
Online adgang:https://www.ebm-journal.org/articles/10.3389/ebm.2025.10540/full
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