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Novel explainable deep learning based drug sensitivity prediction for early treatment of breast cancer

Abstract High-level screening technologies have generated a vast volume of drug-sensitivity data for a panel of cancer cell lines and hundreds of chemicals. By identifying molecular genetic factors of drug sensitivity and developing novel anticancer medicines, computational approaches to analysing t...

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Principais autores: A. Anushya, Awatef Alreshidi, Nallala Hima Varshini, K. Venkatachalam, Seohyun Yoo, Jaehyuk Cho
Format: Artigo
Sprog:Inglês
Udgivet: Nature Portfolio 2026-03-01
Serier:Scientific Reports
Fag:
Breast cancer
Drug discovery
Attention mechanisms
BiLSTM-attention
EDrGAT
Online adgang:https://doi.org/10.1038/s41598-026-44617-y
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