Increased Levels of ICOS and ICOSL Are Associated to Pulmonary Arterial Hypertension in Patients Affected by Connective Tissue Diseases

Background: Pulmonary hypertension (PH) is a life-threatening complication of connective tissue diseases (CTD); in this study, we aimed at investigating the potential role of inducible co-stimulator (ICOS) and its ligand (ICOS-L) as biomarkers of PH in CTD. Materials and Methods: We recruited 109 pa...

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Autori principali:	Mattia Bellan, Francesco Murano, Federico Ceruti, Cristina Piccinino, Stelvio Tonello, Rosalba Minisini, Ailia Giubertoni, Daniele Sola, Roberta Pedrazzoli, Veronica Maglione, Giulia Francesca Manfredi, Antonio Acquaviva, Roberto Piffero, Giuseppe Patti, Mario Pirisi, Pier Paolo Sainaghi
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	MDPI AG 2022-03-01
Serie:	Diagnostics
Soggetti:	ICOS ICOSL pulmonary arterial hypertension systemic sclerosis connective tissue diseases
Accesso online:	https://www.mdpi.com/2075-4418/12/3/704
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