GPCRomics: GPCR Expression in Cancer Cells and Tumors Identifies New, Potential Biomarkers and Therapeutic Targets

G protein-coupled receptors (GPCRs), the largest family of targets for approved drugs, are rarely targeted for cancer treatment, except for certain endocrine and hormone-responsive tumors. Limited knowledge regarding GPCR expression in cancer cells likely has contributed to this lack of use of GPCR-...

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Detalhes bibliográficos

Principais autores:	Paul A. Insel, Krishna Sriram, Shu Z. Wiley, Andrea Wilderman, Trishna Katakia, Thalia McCann, Hiroshi Yokouchi, Lingzhi Zhang, Ross Corriden, Dongling Liu, Michael E. Feigin, Randall P. French, Andrew M. Lowy, Fiona Murray
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2018-05-01
coleção:	Frontiers in Pharmacology
Assuntos:	breast cancer cancer microenvironment chronic lymphocytic leukemia colon cancer GPCR array orphan receptors
Acesso em linha:	https://www.frontiersin.org/article/10.3389/fphar.2018.00431/full
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