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Droplet digital PCR assay for precise determination of FRS2 gene copy number in bladder cancer

Abstract Objective To establish and validate a droplet digital PCR (ddPCR) assay for quantifying FRS2 gene copy number in formalin-fixed paraffin-embedded (FFPE) bladder cancer tissue samples, and to evaluate its analytical performance. Methods The ddPCR assay was developed using FRS2 as the target...

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Hauptverfasser: Jinqian Li, Jiaqi Liang, Yinyan Xu, Wei Tan, Guanzheng Chen, Tong Ou
Format: Artigo
Sprache:Inglês
Veröffentlicht: BMC 2025-07-01
Schriftenreihe:BMC Cancer
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Online-Zugang:https://doi.org/10.1186/s12885-025-14611-0
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