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Two Birds, One Stone: Double Hits on Tumor Growth and Lymphangiogenesis by Targeting Vascular Endothelial Growth Factor Receptor 3

Vascular endothelial growth factor receptor 3 (VEGFR3) has been known for its involvement in tumor-associated lymphangiogenesis and lymphatic metastasis. The VEGFR3 signaling is stimulated by its main cognate ligand, vascular endothelial growth factor C (VEGF-C), which in turn promotes tumor progres...

Ausführliche Beschreibung

Gespeichert in:
Hauptverfasser: Ming-Chuan Hsu, Mei-Ren Pan, Wen-Chun Hung
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI AG 2019-03-01
Schriftenreihe:Cells
Schlagworte:
VEGF-C
VEGFR3
lymphangiogenesis
lymphatic metastasis
Online-Zugang:https://www.mdpi.com/2073-4409/8/3/270
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