Case Report: Identification of a CARD8 variant in all three patients with PFAPA syndrome complicated with Kawasaki disease

BackgroundPeriodic fever, aphthous stomatitis, pharyngitis, and cervical adenitis (PFAPA syndrome), and Kawasaki disease (KD) are both considered to be disorders of the innate immune system, and the potential role of inflammasome activation in the immunopathogenesis of both diseases has been previou...

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Główni autorzy:	Haruhiko Nakamura, Atsuo Kikuchi, Hideyuki Sakai, Miki Kamimura, Yohei Watanabe, Ryoichi Onuma, Jun Takayama, Gen Tamiya, Yoichi Mashimo, Ryota Ebata, Hiromichi Hamada, Tomohiro Suenaga, Yoshihiro Onouchi, Satoru Kumaki
Format:	Artigo
Język:	Inglês
Wydane:	Frontiers Media S.A. 2024-03-01
Seria:	Frontiers in Pediatrics
Hasła przedmiotowe:	CARD8 inflammasome NLRP3 inflammatory dysregulation Kawasaki disease PFAPA syndrome
Dostęp online:	https://www.frontiersin.org/articles/10.3389/fped.2024.1340263/full
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