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Clinical utility of targeted next‐generation sequencing for the diagnosis of myeloid neoplasms with germline predisposition

Myeloid neoplasms (MN) with germline predisposition (MNGP) are likely to be more common than currently appreciated. Many of the genes involved in MNGP are also recurrently mutated in sporadic MN. Therefore, routine analysis of gene panels by next‐generation sequencing provides an effective approach...

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Principais autores: Cristina Andrés‐Zayas, Julia Suárez‐González, Gabriela Rodríguez‐Macías, Nieves Dorado, Santiago Osorio, Patricia Font, Diego Carbonell, María Chicano, Paula Muñiz, Mariana Bastos, Mi Kwon, José Luis Díez‐Martín, Ismael Buño, Carolina Martínez‐Laperche
Format: Artigo
Sprog:Inglês
Udgivet: Wiley 2021-09-01
Serier:Molecular Oncology
Fag:
family history
genetic counseling
hereditary cancer
myeloid neoplasms with germline predisposition
next‐generation sequencing
Online adgang:https://doi.org/10.1002/1878-0261.12921
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