Can BioSAXS detect ultrastructural changes of antifungal compounds in Candida albicans?–an exploratory study

The opportunistic yeast Candida albicans is the most common cause of candidiasis. With only four classes of antifungal drugs on the market, resistance is becoming a problem in the treatment of fungal infections, especially in immunocompromised patients. The development of novel antifungal drugs with...

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Autori principali:	Kai Hilpert, Christoph Rumancev, Jurnorain Gani, Dominic W. P. Collis, Paula Matilde Lopez-Perez, Vasil M. Garamus, Ralf Mikut, Axel Rosenhahn
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Frontiers Media S.A. 2023-07-01
Serie:	Frontiers in Pharmacology
Soggetti:	Candida albicans antifungal peptides antimicrobial peptides BioSAXS SAXS (small-angle X-ray scattering) mode of action (MOA)
Accesso online:	https://www.frontiersin.org/articles/10.3389/fphar.2023.1141785/full
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