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ASPP2 maintains the integrity of mechanically stressed pseudostratified epithelia during morphogenesis

The early embryo maintains its structure in the face of large mechanical stresses during morphogenesis. Here they show that ASPP2 acts to preserve epithelial integrity in regions of high apical tension during early development.

-д хадгалсан:
Үндсэн зохиолчид: Christophe Royer, Elizabeth Sandham, Elizabeth Slee, Falk Schneider, Christoffer B. Lagerholm, Jonathan Godwin, Nisha Veits, Holly Hathrell, Felix Zhou, Karolis Leonavicius, Jemma Garratt, Tanaya Narendra, Anna Vincent, Celine Jones, Tim Child, Kevin Coward, Chris Graham, Marco Fritzsche, Xin Lu, Shankar Srinivas
Формат: Artigo
Хэл сонгох:Inglês
Хэвлэсэн: Nature Portfolio 2022-02-01
Цуврал:Nature Communications
Онлайн хандалт:https://doi.org/10.1038/s41467-022-28590-4
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