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TRAIL Triggers CRAC-Dependent Calcium Influx and Apoptosis through the Recruitment of Autophagy Proteins to Death-Inducing Signaling Complex

Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) selectively kills various cancer cell types, but also leads to the activation of signaling pathways that favor resistance to cell death. Here, we investigated the as yet unknown roles of calcium signaling and autophagy regulatory protei...

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Autori principali: Kelly Airiau, Pierre Vacher, Olivier Micheau, Valerie Prouzet-Mauleon, Guido Kroemer, Mohammad Amin Moosavi, Mojgan Djavaheri-Mergny
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI AG 2021-12-01
Serie:Cells
Soggetti:
ATRA
ATG7
autophagy
cancer
CRAC channels
DISC
Accesso online:https://www.mdpi.com/2073-4409/11/1/57
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