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A real-world pharmacovigilance analysis of potential ototoxicity associated with sacubitril/valsartan based on FDA Adverse Event Reporting System (FAERS)

Abstract Sacubitril/valsartan, a first-in-class angiotensin receptor neprilysin inhibitor, is widely used to treat heart failure. Despite its efficacy, sacubitril/valsartan inevitably causes adverse events such as hypotension, renal dysfunction, hyperkalemia, and angioedema. Sacubitril/valsartan-ass...

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Hlavní autoři: Ning Wang, Haijun Wang, Ying Chen, Yanfeng Wang
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Portfolio 2024-12-01
Edice:Scientific Reports
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On-line přístup:https://doi.org/10.1038/s41598-024-79272-8
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