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Structure of the Large Extracellular Loop of FtsX and Its Interaction with the Essential Peptidoglycan Hydrolase PcsB in <named-content content-type="genus-species">Streptococcus pneumoniae</named-content>

ABSTRACT Streptococcus pneumoniae is a leading killer of infants and immunocompromised adults and has become increasingly resistant to major antibiotics. Therefore, the development of new antibiotic strategies is desperately needed. Targeting bacterial cell division is one such strategy, specificall...

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Principais autores: Britta E. Rued, Martín Alcorlo, Katherine A. Edmonds, Siseth Martínez-Caballero, Daniel Straume, Yue Fu, Kevin E. Bruce, Hongwei Wu, Leiv S. Håvarstein, Juan A. Hermoso, Malcolm E. Winkler, David P. Giedroc
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2019-02-01
Serier:mBio
Fag:
NMR structure
Streptococcus pneumoniae
cell division
peptidoglycan hydrolases
protein-protein interactions
Online adgang:https://journals.asm.org/doi/10.1128/mBio.02622-18
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