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Stable Polymer-Lipid Hybrid Nanoparticles Based on <i>mcl</i>-Polyhydroxyalkanoate and Cationic Liposomes for mRNA Delivery

<b>Background/Objectives:</b> The development of polymer–lipid hybrid nanoparticles (PLNs) is a promising area of research, as it can help increase the stability of cationic lipid carriers. Hybrid PLNs are core–shell nanoparticle structures that combine the advantages of both polymer nanoparticles a...

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Main Authors: Sergey M. Shishlyannikov, Ilya N. Zubkov, Vera V. Vysochinskaya, Nina V. Gavrilova, Olga A. Dobrovolskaya, Ekaterina A. Elpaeva, Mikhail A. Maslov, Andrey Vasin
Format: Artigo
Language:Inglês
Published: MDPI AG 2024-10-01
Series:Pharmaceutics
Subjects:
polymer–lipid nanoparticles
<i>mcl</i>-polyhydroxyalkanoate
cationic liposome
mRNA transfection
ionic strength
Online Access:https://www.mdpi.com/1999-4923/16/10/1305
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