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Production of egg yolk antibody (IgY) against a chimeric protein containing IpaD, StxB, and TolC antigens from Shigella: An investigation of its prophylactic effects against Shiga toxin (Stx) and Shigella dysenteriae in vitro and in vivo

Shigella is a major problem in developing countries. Immunoglobulin Y (IgY) can be used for prophylaxis and neutralize bacteria. The aim of this study was to produce IgY against the chimeric protein containing IpaD, StxB, and TolC antigens from Shigella, investigate its prophylactic and neutralizing...

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Principais autores: Nahal Hadi, Shahram Nazarian, Saber Rouhi, Seyed Edris Hosseini, Javad Fathi
Formato: Artigo
Idioma:Inglês
Publicado: Elsevier 2024-02-01
Series:Heliyon
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Acceso en liña:http://www.sciencedirect.com/science/article/pii/S2405844024023922
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