CV1-secreting sCAR-T cells potentiate the abscopal effect of microwave ablation in heterogeneous tumors

Summary: Microwave ablation (MWA) triggers a weak systemic immune response that leads to the abscopal regression of distant metastases while killing local tumors, known as the abscopal effect. Combining MWA with chimeric antigen receptor (CAR)-T cells demonstrates promise in enhancing the abscopal e...

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Autori principali:	Bihui Cao, Manting Liu, Zecong Xiao, Dongliang Leng, Yubo Zhou, Zhenfeng Zhang, Lu Wang, Xinkun Huang, Qianqian Ni, Wei Cheng, Yehuda G. Assaraf, Qi Zhao, Jia Shen, Kangshun Zhu
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Elsevier 2025-02-01
Serie:	Cell Reports Medicine
Soggetti:	abscopal effect chimeric antigen receptor microwave ablation SIRPα macrophage heterogeneous tumors
Accesso online:	http://www.sciencedirect.com/science/article/pii/S2666379125000382
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