Serum MicroRNA signatures associated with hypertrophic callus formation in polytrauma patients with traumatic brain injury

Abstract Long-bone fractures occasionally develop excessive callus formation in the presence of traumatic brain injury, a clinically relevant but poorly understood injury response. Although this phenomenon is known for decades, the causal factors are still underexplored, and no systemic biomarkers a...

Ausführliche Beschreibung

Bibliografische Detailangaben

Hauptverfasser:	Thomas Lettner, Florian Dussing, Renate Gehwolf, Christian Deininger, Amelie Deluca, Verena Wally, Valeska Hofmann, Matthias Hackl, Andreas Traweger, Florian Wichlas
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Nature Portfolio 2025-12-01
Schriftenreihe:	Scientific Reports
Schlagworte:	Long-bone fracture Traumatic-brain-injury Hypertrophic-callus miRNA DLK1-DIO3 Pituitary gland
Online-Zugang:	https://doi.org/10.1038/s41598-025-27270-9
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