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Biomimetic fractal topography enhances podocyte maturation in vitro

Abstract In their native environment, tissues are organized into intricate fractal structures, rarely recapitulated in their culture in vitro. The extent to which fractal (self-similar) patterns that resemble complex topography in vivo influence cell maturation remain inadequately elucidated. Yet, t...

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Principais autores: Chuan Liu, Praful Aggarwal, Karl T. Wagner, Shira Landau, Teng Cui, Xin Song, Laleh Shamaei, Naimeh Rafatian, Yimu Zhao, Sonia Rodriguez-Ramirez, Keith Morton, Elizabeth Virlee, Chen Yu Li, Dawn Bannerman, Simon Pascual-Gil, Sargol Okhovatian, Anastasia Radisic, Sergi Clotet-Freixas, Teodor Veres, Mohtada Sadrzadeh, Tobin Filleter, Ulrich Broeckel, Ana Konvalinka, Milica Radisic
Formato: Artigo
Idioma:Inglês
Publicado: Nature Portfolio 2025-12-01
Series:Nature Communications
Acceso en liña:https://doi.org/10.1038/s41467-025-66037-8
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