High Level of Aristolochic Acid Detected With a Unique Genomic Landscape Predicts Early UTUC Onset After Renal Transplantation in Taiwan

BackgroundThe unusual high dialysis prevalence and upper urinary tract urothelial carcinoma (UTUC) incidence in Taiwan may attribute to aristolochic acid (AA), which is nephrotoxic and carcinogenic, exposure. AA can cause a unique mutagenic pattern showing A:T to T:A transversions (mutational Signat...

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Үндсэн зохиолчид:	Hong-Yue Lai, Li-Ching Wu, Po-Hsin Kong, Hsin-Hwa Tsai, Yen-Ta Chen, Yuan-Tso Cheng, Hao-Lun Luo, Chien-Feng Li
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	Frontiers Media S.A. 2022-01-01
Цуврал:	Frontiers in Oncology
Нөхцлүүд:	aristolochic acid renal transplantation UTUC LC-MS/MS mTOR biomarker
Онлайн хандалт:	https://www.frontiersin.org/articles/10.3389/fonc.2021.828314/full
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!