Clonal expansion and diversification of germinal center and memory B cell responses to booster immunization in primates

Summary: Effective vaccines elicit B cell clonal expansion in germinal centers (GCs) that produce memory B cells and antibody-secreting plasma cells. In mice, memory B cells rarely re-enter GCs upon boosting and instead differentiate into plasma cells. However, mouse circulating memory constitutes o...

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मुख्य लेखकों:	Lachlan P. Deimel, Yoshiaki Nishimura, Gabriela S. Silva Santos, Viren A. Baharani, Brianna Hernandez, Thiago Y. Oliveira, Andrew J. MacLean, Marie Canis, Sadman Shawraz, Anna Gazumyan, Harald Hartweger, Paul D. Bieniasz, Theodora Hatziioannou, Malcolm A. Martin, Michel C. Nussenzweig
स्वरूप:	Artigo
भाषा:	Inglês
प्रकाशित:	Elsevier 2025-08-01
श्रृंखला:	Cell Reports
विषय:	CP: Immunology
ऑनलाइन पहुंच:	http://www.sciencedirect.com/science/article/pii/S2211124725009131
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