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TSS-Seq analysis of low pH-induced gene expression in intercalated cells in the renal collecting duct.

Metabolic acidosis often results from chronic kidney disease; in turn, metabolic acidosis accelerates the progression of kidney injury. The mechanisms for how acidosis facilitates kidney injury are not fully understood. To investigate whether low pH directly affects the expression of genes controlli...

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Библиографические подробности
Главные авторы: Yuichiro Izumi, Hideki Inoue, Yushi Nakayama, Koji Eguchi, Yukiko Yasuoka, Naomi Matsuo, Hiroshi Nonoguchi, Yutaka Kakizoe, Takashige Kuwabara, Masashi Mukoyama
Формат: Artigo
Язык:Inglês
Опубликовано: Public Library of Science (PLoS) 2017-01-01
Серии:PLoS ONE
Online-ссылка:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0184185&type=printable
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