Anti-BCL2 therapy eliminates giant congenital melanocytic nevus by senolytic and immune induction

Abstract Giant congenital melanocytic nevus (GCMN) is a RAS/RAF mutation-driven syndrome characterized by extensive melanocytic lesions, posing psychological challenges and a lifelong risk of malignancy. Existing treatments like surgical resection and laser therapy fail to fully remove lesions, and...

ver descrição completa

Detalhes bibliográficos

Principais autores:	Boxuan Wei, Qingxiong Yu, Jiamin Jin, Danli Zhu, Bohan Lai, Jieyu Gu, Ran Yang, Huailiang Huang, Hongzhan Lin, Liang Zhang, Tao Zan, Feng Xie, Kang Zhang, Qingfeng Li
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Nature Publishing Group 2025-05-01
coleção:	Signal Transduction and Targeted Therapy
Acesso em linha:	https://doi.org/10.1038/s41392-025-02247-2
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!