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Engrailed-2 promotes a malignant phenotype of esophageal squamous cell carcinoma through upregulating the expression of pro-oncogenic genes

Background A number of homeobox genes have been implicated in the development of various cancers. However, the role of engrailed 2 (EN2), a member of the homeobox gene superfamily, in esophageal squamous cell carcinoma (ESCC) remains unknown. Methods The expression of EN2 was examined using quantita...

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Principais autores: Yong Cao, Xiaoyan Wang, Li Tang, Yan Li, Xueqin Song, Xu Liu, Mingying Li, Feng Chen, Haisu Wan
Format: Artigo
Sprog:Inglês
Udgivet: PeerJ Inc. 2020-02-01
Serier:PeerJ
Fag:
Engrailed 2
SPARC
EN2 mutant
Esophageal squamous cell carcinoma
Malignant phenotype
Online adgang:https://peerj.com/articles/8662.pdf
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