Antimicrobial Peptide Mastoparan-AF Kills Multi-Antibiotic Resistant <i>Escherichia coli</i> O157:H7 via Multiple Membrane Disruption Patterns and Likely by Adopting 3–11 Amphipathic Helices to Favor Membrane Interaction

We investigated the antimicrobial activity and membrane disruption modes of the antimicrobial peptide mastoparan-AF against hemolytic <i>Escherichia coli</i> O157:H7. Based on the physicochemical properties, mastoparan-AF may potentially adopt a 3–11 amphipathic helix-type structure, with five to se...

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Bibliografische Detailangaben

Hauptverfasser:	Chun-Hsien Lin, Ching-Lin Shyu, Zong-Yen Wu, Chao-Min Wang, Shiow-Her Chiou, Jiann-Yeu Chen, Shu-Ying Tseng, Ting-Er Lin, Yi-Po Yuan, Shu-Peng Ho, Kwong-Chung Tung, Frank Chiahung Mao, Han-Jung Lee, Wu-Chun Tu
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	MDPI AG 2023-02-01
Schriftenreihe:	Membranes
Schlagworte:	antibiotic resistance antimicrobial peptide <i>Escherichia coli</i> O157:H7 mastoparan-AF membrane disruption pattern membrane permeabilization
Online-Zugang:	https://www.mdpi.com/2077-0375/13/2/251
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