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Association between gut microbiota and CpG island methylator phenotype in colorectal cancer

The intestinal microbiota is an important environmental factor implicated in CRC development. Intriguingly, modulation of DNA methylation by gut microbiota has been reported in preclinical models, although the relationship between tumor-infiltrating bacteria and CIMP status is currently unexplored....

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Main Authors: Pyoung Hwa Park, Kelsey Keith, Gennaro Calendo, Jaroslav Jelinek, Jozef Madzo, Raad Z. Gharaibeh, Jayashri Ghosh, Carmen Sapienza, Christian Jobin, Jean-Pierre J. Issa
Format: Artigo
Language:Inglês
Published: Taylor & Francis Group 2024-12-01
Series:Gut Microbes
Subjects:
Gut microbiota
Colorectal cancer
CpG island methylator phenotype
DNA methylation
Epigenetics
Online Access:https://www.tandfonline.com/doi/10.1080/19490976.2024.2363012
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