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Epigenetic and biological age acceleration in children with atopic dermatitis

Background: Atopic dermatitis (AD) is a chronic inflammatory skin disease resulting from the complex interplay of genetic and environmental factors, meriting exploration using temporally dynamic biomarkers. DNA methylation–based algorithms have been trained to accurately estimate biological age, and...

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Principais autores: Richie Jeremian, PhD, Alexandra Malinowski, PhD, Edward S. Oh, PhD, Melinda Gooderham, MD, MSc, FRCPC, Cathryn Sibbald, MD, MSc, FRCPC, Jensen Yeung, MD, FRCPC, Yuka Asai, MD, FRCPC, Vincent Piguet, MD, PhD, FRCP, Carolyn S. Jack, MDCM, PhD, FRCPC
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2024-08-01
coleção:Journal of Allergy and Clinical Immunology: Global
Assuntos:
Atopic dermatitis
DNA methylation
epigenetic aging
biological aging
inflammatory biomarkers
Acesso em linha:http://www.sciencedirect.com/science/article/pii/S2772829324000717
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