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Preparation of Messenger RNA Nanomicelles via Non-Cytotoxic PEG-Polyamine Nanocomplex for Intracerebroventicular Delivery: A Proof-of-Concept Study in Mouse Models

The specific delivery of messenger RNA (mRNA) is an excellent alternative to plasmid DNA, due to the latter’s potential risk for random integration into the host genome. In this study, we propose the use of specially tailored polyplex nanomicelles for the intravenous delivery of mRNA into the...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Long Yi Chan, Yit Lung Khung, Chin-Yu Lin
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: MDPI AG 2019-01-01
Cyfres:Nanomaterials
Pynciau:
Mynediad Ar-lein:http://www.mdpi.com/2079-4991/9/1/67
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!