Impact of tension-free autograft repair on early sensory recovery in polyethylene glycol (PEG)-mediated axonal fusion following traumatic peripheral nerve injuries

Abstract Autograft repairs remain inferior to primary neurorrhaphy, largely due to axonal regeneration across two coaptation sites. PEG–mediated neurorrhaphy has been shown to enhance recovery following peripheral nerve injury by mitigating Wallerian degeneration. Whether PEG can overcome these limi...

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Principais autores:	Barite Gutama, Ronald M. Cornely, Ricardo A. Torres-Guzman, Sriya Nemani, Franklin Gergoudis, Benjamin Savitz, Anthony Hoang, Huseyin Karagoz, Douglas R. Weikert, Yusha Katie Liu, Lesley Wong, Feng Zhang, Panambur L. Bhandari, William Lineaweaver, Brian C. Drolet, Shady Elmaraghi, J. Bradford Hill, Wesley P. Thayer
Format:	Artigo
Jezik:	Inglês
Izdano:	Nature Portfolio 2026-05-01
Serija:	Scientific Reports
Teme:	Peripheral nerve injury Polyethylene glycol (PEG) Axonal fusion Neurorrhaphy Nerve autograft Sensory recovery
Online dostop:	https://doi.org/10.1038/s41598-026-52000-0
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