Single-cell transcriptomics reveals lipid metabolism reprogramming in macrophages in vitro during early stages of Leishmania donovani infection

Abstract Background Leishmania donovani can cause visceral leishmaniasis, clinically manifested as fever, hepatosplenomegaly, and anemia. If left untreated, it may lead to death owing to complications from other diseases and infections. However, the pathogenesis of L. donovani infection remains uncl...

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Detalhes bibliográficos

Principais autores:	Fei-Ran Li, Qi Sun, Qing Wang, Ling-Lin Qu, Zhi-Hui Li, Zheng-Jun Yi, Bin-Bin Yang
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2026-03-01
coleção:	Parasites & Vectors
Assuntos:	Leishmaniasis Leishmania donovani Macrophages Single-cell RNA sequencing Infection mechanism
Acesso em linha:	https://doi.org/10.1186/s13071-026-07361-w
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