Designing herpes viruses as oncolytics
Oncolytic herpes simplex virus (oHSV) was one of the first genetically-engineered oncolytic viruses. Because HSV is a natural human pathogen that can cause serious disease, it is incumbent that it can be genetically-engineered or significantly attenuated for safety. Here, we present a detailed expla...
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| Hauptverfasser: | , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Elsevier
2015-01-01
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| Schriftenreihe: | Molecular Therapy: Oncolytics |
| Online-Zugang: | http://www.sciencedirect.com/science/article/pii/S2372770516300122 |
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