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Waste to worth: diagnostic accuracy of Xpert MTB/XDR on contaminated liquid cultures to salvage the detection of drug-resistant tuberculosis

ABSTRACT Mycobacterium Growth Indicator Tube (MGIT) 960 culture is critical for tuberculosis (TB) drug susceptibility testing (DST) but is vulnerable to contamination. We evaluated the accuracy of Xpert MTB/XDR, a molecular DST for isoniazid, fluoroquinolone, amikacin, and ethionamide, on to-be-disc...

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Principais autores: Yonas Ghebrekristos, Erick Auma, Zama Mahlobo, Rouxjeane Venter, Natalie Beylis, Jay Achar, Brigitta Derendinger, Sarishna Singh, Megan Burger, Christoffel Opperman, Robin Warren, Grant Theron
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2025-08-01
Serier:Journal of Clinical Microbiology
Fag:
Xpert MTB/XDR
contaminated cultures
drug susceptibility testing
tuberculosis
Online adgang:https://journals.asm.org/doi/10.1128/jcm.00580-25
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