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Hepatitis C virus modified SE2F442NYT-mRNA-LNP candidate vaccine promotes helper CXCR5+T cells

ABSTRACT T cells play an important role in initiating antibody responses by instructive signals of cell-cell contacts and secretion of soluble cytokines as mediators. We investigated the role of the modified soluble E2 (sE2F442NYT) antigen from hepatitis C virus (HCV) on healthy human peripheral blo...

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Bibliografische Detailangaben
Hauptverfasser: Yuki Haga, Preedia Babu E, Marzena Swiderska-Syn, Erin K. Reagan, Drew Weissman, Ranjit Ray
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2025-10-01
Schriftenreihe:Journal of Virology
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Online-Zugang:https://journals.asm.org/doi/10.1128/jvi.01355-25
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