Nitric oxide destabilizes Pias3 and regulates sumoylation.

Small ubiquitin-related protein modifiers (SUMO) modification is an important mechanism for posttranslational regulation of protein function. However, it is largely unknown how the sumoylation pathway is regulated. Here, we report that nitric oxide (NO) causes global hyposumoylation in mammalian cel...

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Autors principals:	Jing Qu, Guang-Hui Liu, Kaiyuan Wu, Peiwei Han, Peng Wang, Jiangmei Li, Xu Zhang, Chang Chen
Format:	Artigo
Idioma:	Inglês
Publicat:	Public Library of Science (PLoS) 2007-10-01
Col·lecció:	PLoS ONE
Accés en línia:	http://europepmc.org/articles/PMC2064872?pdf=render
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