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Primary pathologic role of interleukin-6 in rheumatoid arthritis

BACKGROUND Interleukin-6 (IL-6) is a polyfunctional cytokine that regulates a very large number of cellular activities. Its implication in acute-phase reactant production by hepatocytes is of particular interest, as is its involvement in chronic inflammatory diseases, mainly rheumatoid arthritis, Cr...

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Principais autores: G.L. Bajocchi, N. Pipitone, P.L. Boiardi, C. Salvarani
Format: Artigo
Sprog:Inglês
Udgivet: PAGEPress Publications 2013-05-01
Serier:Italian Journal of Medicine
Fag:
Interleukin-6
Signal transduction
Rheumatoid arthritis
Tocilizumab.
Online adgang:http://www.italjmed.org/index.php/ijm/article/view/294
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