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Immunopathological characterization of ovarian teratomas associated with anti-N-methyl-D-aspartate receptor encephalitis

Abstract Encephalitis with anti-NMDAR antibodies (NMDAR-E) is a severe autoimmune neurological disorder, defined by a clinical presentation of encephalitis and the presence of IgG targeting the GluN1 subunit of NMDA receptors in the CSF. An underlying ovarian teratoma is commonly associated with thi...

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Main Authors: Aude Chefdeville, Isabelle Treilleux, Marie-Eve Mayeur, Coline Couillault, Géraldine Picard, Chloé Bost, Karima Mokhtari, Alexandre Vasiljevic, David Meyronet, Véronique Rogemond, Dimitri Psimaras, Bertrand Dubois, Jérôme Honnorat, Virginie Desestret
Format: Artigo
Language:Inglês
Published: BMC 2019-03-01
Series:Acta Neuropathologica Communications
Subjects:
Ovarian teratoma
Anti-NMDAR encephalitis
Autoimmunity
Online Access:http://link.springer.com/article/10.1186/s40478-019-0693-7
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