Modification of Mesenchymal Stem/Stromal Cell-Derived Small Extracellular Vesicles by Calcitonin Gene Related Peptide (CGRP) Antagonist: Potential Implications for Inflammation and Pain Reversal

During the progression of knee osteoarthritis (OA), the synovium and infrapatellar fat pad (IFP) can serve as source for Substance P (SP) and calcitonin gene-related peptide (CGRP), two important pain-transmitting, immune, and inflammation modulating neuropeptides. Our previous studies showed that i...

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Автори:	Kevin Liebmann, Mario A. Castillo, Stanislava Jergova, Thomas M. Best, Jacqueline Sagen, Dimitrios Kouroupis
Формат:	Artigo
Мова:	Inglês
Опубліковано:	MDPI AG 2024-03-01
Серія:	Cells
Предмети:	mesenchymal stem/stromal cells (MSC) synovium infrapatellar fat pad (IFP) CD10 (neprilysin) calcitonin gene-related peptide (CGRP) small extracellular vesicles (sEVs)
Онлайн доступ:	https://www.mdpi.com/2073-4409/13/6/484
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