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L-Type Amino Acid Transporter 1 (LAT1) Promotes PMA-Induced Cell Migration through mTORC2 Activation at the Lysosome

The mTOR signaling pathway integrates signaling inputs from nutrients, including glucose and amino acids, which are precisely regulated by transporters depending on nutrient levels. The L-type amino acid transporter 1 (LAT1) affects the activity of mTORC1 through upstream regulators that sense intra...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Hauptverfasser: Kun Tae, Sun-Jick Kim, Sang-Woo Cho, Hoyeon Lee, Hyo-Sun Cha, Cheol-Yong Choi
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI AG 2023-10-01
Schriftenreihe:Cells
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Online-Zugang:https://www.mdpi.com/2073-4409/12/20/2504
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