KIR in Allogeneic Hematopoietic Stem Cell Transplantation: Need for a Unified Paradigm for Donor Selection

Allogeneic hematopoietic stem cell transplantation (aHSCT) is a lifesaving therapy for hematological malignancies. For years, a fully matched HLA donor was a requisite for the procedure. However, new immunosuppressive strategies have enabled the recruitment of viable alternative donors, particularly...

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Principais autores:	Adèle Dhuyser, Alice Aarnink, Michaël Pérès, Jyothi Jayaraman, Neda Nemat-Gorgani, Marie Thérèse Rubio, John Trowsdale, James Traherne
格式:	Artigo
語言:	Inglês
出版:	Frontiers Media S.A. 2022-02-01
叢編:	Frontiers in Immunology
主題:	killer immunoglobulin-like receptors (KIR) allogeneic hematopoietic stem cell transplantation (aHSCT) Donor selection alloreactivity potential predictive model
在線閱讀:	https://www.frontiersin.org/articles/10.3389/fimmu.2022.821533/full
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