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Effects of imidazole derivatives on cellular proliferation and apoptosis in myeloid leukemia

Abstract Background Acute promyelocytic leukemia (APL) is the sub-type of Acute myeloid leukemia (AML) which is described by differentiation block at promyelocytic stage and t(15; 17) translocation with All trans retinoic acid (ATRA) and arsenic trioxide (ATO) as standard treatments. Chronic myeloid...

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Main Authors: Bazla Binte Nadeem, Aysha Bibi, Mudassir Khan, Gul Rukh Sajjad, Fazal Adnan, Zaheer Ahmad, Dilawar Khan
Format: Artigo
Language:Inglês
Published: BMC 2024-09-01
Series:BMC Cancer
Subjects:
Leukemia
Imidazole
Cancer therapy
Online Access:https://doi.org/10.1186/s12885-024-12958-4
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