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Plasma biomarkers identify brain ATN abnormalities in a dementia-free population-based cohort

Abstract Introduction Using the ATN framework, we evaluated the potential of plasma biomarkers to identify abnormal brain amyloid-beta (Aβ) positron emission tomography (PET), tau-PET and neurodegeneration in a socioeconomically disadvantaged population-based cohort. Methods Community-dwelling demen...

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Principais autores: Menayit Tamrat Dresse, Pamela C. L. Ferreira, Akshay Prasadan, Jihui L. Diaz, Xuemei Zeng, Bruna Bellaver, Guilherme Povala, Victor L. Villemagne, M. Ilyas Kamboh, Ann D. Cohen, Tharick A. Pascoal, Mary Ganguli, Beth E. Snitz, C. Elizabeth Shaaban, Thomas K. Karikari
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2025-07-01
Serier:Alzheimer’s Research & Therapy
Fag:
Amyloid beta
Tau pathology
Neurodegeneration
Neuroimaging
ATN framework
P-tau217
Online adgang:https://doi.org/10.1186/s13195-025-01803-w
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